Advances in the Discovery of Small-Molecule IRAK4 Inhibitors
Author:
Publisher
Elsevier
Reference54 articles.
1. IRAK-4: A novel member of the IRAK family with the properties of an IRAK-kinase
2. Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling
3. Selective predisposition to bacterial infections in IRAK-4–deficient children: IRAK-4–dependent TLRs are otherwise redundant in protective immunity
4. Infectious Diseases in Patients with IRAK-4, MyD88, NEMO, or IκBα Deficiency
5. IRAK-4 kinase activity is required for IRAK-4-dependent innate and adaptive immune responses
Cited by 21 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839;Journal of Medicinal Chemistry;2024-01-17
2. Emerging trends in IRAK-4 kinase research;Molecular Biology Reports;2023-07-25
3. Binding Energy Partition of Promising IRAK‐4 Inhibitor (Zimlovisertib) for the Treatment of COVID‐19 Pneumonia;ChemPhysChem;2022-10-18
4. Pyrrole–Aminopyrimidine Ensembles: Cycloaddition of Guanidine to Acylethynylpyrroles;Molecules;2021-03-17
5. Long noncoding RNA IRL regulates NF-κB-mediated immune responses through suppression of miR-27c-3p-dependent IRAK4 downregulation in teleost fish;Journal of Biological Chemistry;2021-01
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