Optimization of multi flow rate loading strategy for process intensification of Protein A chromatography

Author:

Ramakrishna AnjaliORCID,Maranholkar Vijay,Hadpe Sandeep,Iyer Jyoti,Rathore AnuragORCID

Publisher

Elsevier BV

Reference17 articles.

1. The increasingly human and profitable monoclonal antibody market;Grilo;Trends Biotechnol.,2019

2. Re-use of protein A resin: fouling and economics;Rathore;BioPharm. Int.,2015

3. Contribution of protein A step towards cost of goods for continuous production of monoclonal antibody therapeutics;Bansode;J. Chem. Technol. Biotechnol.,2021

4. The impact of continuous multicolumn chromatography on biomanufacturing efficiency;Bisschops;Pharm. Bioprocess.,2013

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1. Use of Industrial Scale Chromatography in Pharmaceutical Discovery/Manufacturing;Reference Module in Chemistry, Molecular Sciences and Chemical Engineering;2024

2. Process intensification in biopharmaceutical process development and production – an industrial perspective;Physical Sciences Reviews;2023-11-13

3. Sensors and chemometrics in downstream processing;Biotechnology and Bioengineering;2023-07-20

4. Factors affecting therapeutic protein purity and yield during chromatographic purification;Preparative Biochemistry & Biotechnology;2023-05-26

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