Production of metabolites of the anti-cancer drug noscapine using a P450BM3 mutant library-Reference-Cited by-同舟云学术

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Production of metabolites of the anti-cancer drug noscapine using a P450BM3 mutant library

Published:2019-12 Issue: Volume:24 Page:e00372
ISSN:2215-017X
Container-title:Biotechnology Reports
language:en
Short-container-title:Biotechnology Reports

Author:

Richards Luke,Lutz Adrian,Chalmers David K.,Jarrold Ailsa,Bowser Tim,Stevens Geoffrey W.,Gras Sally L.

Funder

Sun Pharmaceutical Industries Ltd

The University of Melbourne

Australian Government Research Training Program Scholarship

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,Biotechnology

Reference56 articles.

1. Extending the application of biocatalysis to meet the challenges of drug development;Devine;Nat. Rev. Chem.,2018

2. Progress toward the development of noscapine and derivatives as anticancer agents;DeBono;J. Med. Chem.,2015

3. Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells;Ye;Proc. Natl. Acad. Sci. U.S.A.,1998

4. Toxicity studies on noscapine;Winter;Toxicol. Appl. Pharmacol.,1961

5. Noscapine inhibits tumor growth with little toxicity to normal tissues or inhibition of immune responses;Ke;Cancer Immunol. Immunother.,2000

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