Progress Toward the Development of Noscapine and Derivatives as Anticancer Agents

Author:

DeBono Aaron1,Capuano Ben1,Scammells Peter J.1

Affiliation:

1. Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus), 381 Royal Parade, Parkville, Victoria 3052 Australia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference146 articles.

1. Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells

2. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

3. Ho, W.; Shubhada, S.; Mills, L.; Negrello, T.; Hao, M.; Connell, E.Cancer in Australia: An Overview 2012;Australian Institute of Health and Welfare & Australasian Association of Cancer Registries:Canberra, 2012; no. 74, pp1–215

4. Microtubules and resistance to tubulin-binding agents

5. The spindle: a dynamic assembly of microtubules and motors

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