Identification of Structural Mechanisms of HIV-1 Protease Specificity Using Computational Peptide Docking: Implications for Drug Resistance
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Structural Biology
Reference61 articles.
1. HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants;Altman;J. Am. Chem. Soc.,2008
2. Computational design and experimental study of tighter binding peptides to an inactivated mutant of HIV-1 protease;Altman;Proteins,2008
3. Amino acid preferences for a critical substrate binding subsite of retroviral proteases in type 1 cleavage sites;Bagossi;J. Virol.,2005
4. Molecular basis for the relative substrate specificity of human immunodeficiency virus type 1 and feline immunodeficiency virus proteases;Beck;J. Virol.,2001
5. Defining HIV-1 protease substrate selectivity;Beck;Curr. Drug Targets,2002
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