Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8-Reference-Cited by-同舟云学术

Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8

Published:2022-03 Issue: Volume:24 Page:88-101
ISSN:2329-0501
Container-title:Molecular Therapy - Methods & Clinical Development
language:en
Short-container-title:Molecular Therapy - Methods & Clinical Development

Author:

Cabanes-Creus Marti^ORCID,Navarro Renina Gale^ORCID,Zhu Erhua,Baltazar Grober,Liao Sophia H.Y.,Drouyer Matthieu^ORCID,Amaya Anais K.^ORCID,Scott Suzanne^ORCID,Nguyen Loan Hanh,Westhaus Adrian^ORCID,Hebben Matthias^ORCID,Wilson Laurence O.W.,Thrasher Adrian J.,Alexander Ian E.^ORCID,Lisowski Leszek^ORCID

Funder

National Health and Medical Research Council

National Science Centre Poland

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference43 articles.

1. Clades of Adeno-associated viruses are widely disseminated in human tissues;Gao;J. Virol.,2004

2. The assembly-activating protein promotes capsid assembly of different adeno-associated virus serotypes;Sonntag;J. Virol.,2011

3. Comprehensive AAV capsid fitness landscape reveals a viral gene and enables machine-guided design;Ogden;Science,2019

4. Adeno-associated virus capsid assembly is divergent and stochastic;Worner;Nat. Commun.,2021

5. Adeno-associated virus structural biology as a tool in vector development;Drouin;Future Virol.,2013

Cited by 26 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Enhanced AAV transduction across preclinical CNS models: A comparative study in human brain organoids with cross-species evaluations;Molecular Therapy - Nucleic Acids;2024-09

2. Sleeping Beauty mRNA-LNP enables stable rAAV transgene expression in mouse and NHP hepatocytes and improves vector potency;Molecular Therapy;2024-07

3. AAV-delivered hepato-adrenal cooperativity in steroidogenesis: Implications for gene therapy for congenital adrenal hyperplasia;Molecular Therapy - Methods & Clinical Development;2024-06

4. Novel AAV variants with improved tropism for human Schwann cells;Molecular Therapy - Methods & Clinical Development;2024-06

5. AAV Capsid Screening for Translational Pig Research Using a Mouse Xenograft Liver Model;2024-05-29