Characterizing the cellular immune response to subretinal AAV gene therapy in the murine retina-Reference-Cited by-同舟云学术

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Characterizing the cellular immune response to subretinal AAV gene therapy in the murine retina

Published:2021-09 Issue: Volume:22 Page:52-65
ISSN:2329-0501
Container-title:Molecular Therapy - Methods & Clinical Development
language:en
Short-container-title:Molecular Therapy - Methods & Clinical Development

Author:

Chandler Laurel C.,McClements Michelle E.,Yusuf Imran H.,Martinez-Fernandez de la Camara Cristina,MacLaren Robert E.,Xue Kanmin

Funder

Wellcome Trust

NIHR Oxford Biomedical Research Centre

Medical Research Council

Fight for Sight

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference53 articles.

1. Immune Responses to Viral Gene Therapy Vectors;Shirley;Mol. Ther.,2020

2. Long-term effect of gene therapy on Leber’s congenital amaurosis;Bainbridge;N. Engl. J. Med.,2015

3. Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial;Russell;Lancet,2017

4. Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial;MacLaren;Lancet,2014

5. Visual Acuity after Retinal Gene Therapy for Choroideremia;Edwards;N. Engl. J. Med.,2016

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Clinical and Ocular Inflammatory Inhibitors of Viral-Based Gene Therapy of the Retina;Acta Microbiologica Hellenica;2024-09-11

2. Genetic therapies and potential therapeutic applications of CRISPR activators in the eye;Progress in Retinal and Eye Research;2024-09

3. Adeno-Associated Virus Vectors—a Target of Cellular and Humoral Immunity—are Expanding Their Reach Toward Hematopoietic Stem Cell Modification and Immunotherapies;Human Gene Therapy;2024-08-28

4. Single-cell transcriptomic analysis of retinal immune regulation and blood-retinal barrier function during experimental autoimmune uveitis;Scientific Reports;2024-08-28

5. The AAV2.7m8 capsid packages a higher degree of heterogeneous vector genomes than AAV2;Gene Therapy;2024-08-12

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