Development of a method to measure free and bound ropivacaine in human plasma using equilibrium dialysis and Hydrophilic interaction chromatography coupled to high resolution mass spectrometry
Author:
Publisher
Elsevier BV
Subject
Analytical Chemistry
Reference15 articles.
1. Lloyd, T. (2012). Techniques for Determining Protein Binding in Drug Discovery and Development. ADME-Enabling Technologies in Drug Design and Development, p. 177.
2. Determination of the free concentration of ropivacaine in plasma by packed capillary liquid chromatography: A comparison of ultrafiltration and microdialysis as sample preparation methods
3. Chromatographic analysis of local anesthetics in biological samples
4. Evaluation of high-performance liquid chromatography and mass spectrometry method for pharmacokinetic study of local anesthetic ropivacaine in plasma
5. Population pharmacokinetic analysis of ropivacaine and its metabolite 2′,6′-pipecoloxylidide from pooled data in neonates, infants, and children
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3. Sample preparation techniques for protein binding measurement in radiopharmaceutical approaches: A short review;Talanta;2020-11
4. Validation according to European and American regulatory agencies guidelines of an LC-MS/MS method for the quantification of free and total ropivacaine in human plasma;Clinical Chemistry and Laboratory Medicine (CCLM);2020-04-28
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