Targeting the AKT/GSK3β/Cyclin D1/Cdk4 Survival Signaling Pathway for Eradication of Tumor Radioresistance Acquired by Fractionated Radiotherapy-Reference-Cited by-同舟云学术

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Targeting the AKT/GSK3β/Cyclin D1/Cdk4 Survival Signaling Pathway for Eradication of Tumor Radioresistance Acquired by Fractionated Radiotherapy

Published:2011-06 Issue:2 Volume:80 Page:540-548
ISSN:0360-3016
Container-title:International Journal of Radiation Oncology*Biology*Physics
language:en
Short-container-title:International Journal of Radiation Oncology*Biology*Physics

Author:

Shimura Tsutomu,Kakuda Satoshi,Ochiai Yasushi,Kuwahara Yoshikazu,Takai Yoshihiro,Fukumoto Manabu

Publisher

Elsevier BV

Subject

Cancer Research,Radiology Nuclear Medicine and imaging,Oncology,Radiation

Reference23 articles.

1. Repopulation of cancer cells during therapy: An important cause of treatment failure;Kim;Nat Rev Cancer,2005

2. Acquired radioresistance of human tumor cells by DNA-PK/AKT/GSK3 beta-mediated cyclin D1 overexpression;Shimura;Oncogene,2010

3. Increased expression of pAKT is associated with radiation resistance in cervical cancer;Kim;Br J Cancer,2006

4. Serine/threonine kinase AKT is frequently activated in human bile duct cancer and is associated with increased radioresistance;Tanno;Cancer Res,2004

5. Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer;Bussink;Lancet Oncol,2008

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2. A perspective on tumor radiation resistance following high-LET radiation treatment;Journal of Cancer Research and Clinical Oncology;2024-05-02

3. Nuclear DNA damage-triggered ATM-dependent AMPK activation regulates the mitochondrial radiation response;International Journal of Radiation Biology;2024-01-03

4. Fractionated radiation exposure enhances the DNA repair capacity to acquire radioresistance in HCT8 human colorectal cancer cells;International Journal of Radiation Research;2023-10-01

5. Impact of AKT1 on cell invasion and radiosensitivity in a triple negative breast cancer cell line developing brain metastasis;Frontiers in Oncology;2023-07-06

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