Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage-Reference-Cited by-同舟云学术

Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

Published:2018-09 Issue:5 Volume:71 Page:745-760.e5
ISSN:1097-2765
Container-title:Molecular Cell
language:en
Short-container-title:Molecular Cell

Author:

Dunphy Gillian,Flannery Sinéad M.,Almine Jessica F.,Connolly Dympna J.,Paulus Christina,Jønsson Kasper L.,Jakobsen Martin R.,Nevels Michael M.,Bowie Andrew G.,Unterholzner Leonie^ORCID

Funder

Medical Research Council

North West Cancer Research

European Commission

Science Foundation Ireland

NIH

Danish Council for Independent Research

Lundbeck Foundation

Aase og Ejnar Danielsens Fond

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference51 articles.

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2. A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway;Aglipay;Oncogene,2003

3. IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes;Almine;Nat. Commun.,2017

4. Enhanced phosphorylation of p53 by ATM in response to DNA damage;Banin;Science,1998

5. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line;Boukamp;J. Cell Biol.,1988

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