β-sitosterol alleviates pulmonary arterial hypertension by altering smooth muscle cell phenotype and DNA damage/cGAS/STING signaling

Author:

Li Jing,Meng Zhong-Yuan,Wen Hong,Lu Chuang-Hong,Qin Yue,Xie Yi-Ming,Chen QiORCID,Lv Jin-HuiORCID,Huang Feng,Zeng Zhi-Yu

Publisher

Elsevier BV

Reference39 articles.

1. Cgas in action: expanding roles in immunity and inflammation;Ablasser;Science,2019

2. An update on beta-sitosterol: a potential herbal nutraceutical for diabetic management;Babu;Biomed. Pharmacother.,2020

3. Mitochondrial damage-induced innate immune activation in vascular smooth muscle cells promotes chronic kidney disease-associated plaque vulnerability;Bi;Adv. Sci.,2021

4. The cancer theory of pulmonary arterial hypertension;Boucherat;Pulm. Circ.,2017

5. Network pharmacology analysis, molecular docking integrated experimental verification reveal β-sitosterol as the active anti-nsclc ingredient of polygonatum cyrtonema hua by suppression of Pi3k/Akt/Hif-1α signaling pathway;Cao;J. Ethnopharmacol.,2024

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