The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79-Reference-Cited by-同舟云学术

The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79

Published:2015-10 Issue:2 Volume:60 Page:319-327
ISSN:1097-2765
Container-title:Molecular Cell
language:en
Short-container-title:Molecular Cell

Author:

Chen Shoudeng,Yang Ze,Wilkinson Alex W.,Deshpande Aniruddha J.,Sidoli Simone,Krajewski Krzysztof,Strahl Brian D.,Garcia Benjamin A.,Armstrong Scott A.,Patel Dinshaw J.,Gozani Or

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference40 articles.

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3. Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l;Chen;Leukemia,2013

4. Potent inhibition of DOT1L as treatment of MLL-fusion leukemia;Daigle;Blood,2013

5. Chromatin modifications as therapeutic targets in MLL-rearranged leukemia;Deshpande;Trends Immunol.,2012

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