Cilia-Associated Oxysterols Activate Smoothened-Reference-Cited by-同舟云学术

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Cilia-Associated Oxysterols Activate Smoothened

Published:2018-10 Issue:2 Volume:72 Page:316-327.e5
ISSN:1097-2765
Container-title:Molecular Cell
language:en
Short-container-title:Molecular Cell

Author:

Raleigh David R.,Sever Navdar,Choksi Pervinder K.,Sigg Monika Abedin,Hines Kelly M.,Thompson Bonne M.,Elnatan Daniel,Jaishankar Priyadarshini,Bisignano Paola,Garcia-Gonzalo Francesc R.,Krup Alexis Leigh,Eberl Markus,Byrne Eamon F.X.,Siebold Christian,Wong Sunny Y.,Renslo Adam R.,Grabe Michael,McDonald Jeffrey G.,Xu Libin,Beachy Philip A.,Reiter Jeremy F.

Funder

NIH

UCSF Physician Scientist Scholar Program

American Society of Clinical Oncology

Rally Foundation for Childhood Cancer Research

American Brain Tumor Association

NIH program Project Grant to Molecular Genetics

Cancer Research UK

European Research Council

Ludwig Cancer Institute

Howard Hughes Medical Institute

Burroughs Wellcome Fund

Packard Foundation

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference54 articles.

1. Reduced cholesterol levels impair Smoothened activation in Smith-Lemli-Opitz syndrome;Blassberg;Hum. Mol. Genet.,2016

2. The mechanisms of Hedgehog signalling and its roles in development and disease;Briscoe;Nat. Rev. Mol. Cell Biol.,2013

3. Structural basis of Smoothened regulation by its extracellular domains;Byrne;Nature,2016

4. Modulation of ciliary phosphoinositide content regulates trafficking and Sonic Hedgehog signaling output;Chávez;Dev. Cell,2015

5. Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened;Chen;Genes Dev.,2002

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1. Cilia-enriched oxysterol 7β,27-DHC is required for polycystin ion channel activation;Nature Communications;2024-07-31

2. A novel indole derivative, 2‐{3‐[1‐(benzylsulfonyl)piperidin‐4‐yl]‐2‐methyl‐1H‐indol‐1‐yl}‐1‐(pyrrolidin‐1‐yl)ethenone, suppresses hedgehog signaling and drug‐resistant tumor growth;Archiv der Pharmazie;2024-07-04

3. Sonic Hedgehog activates prostaglandin signaling to stabilize primary cilium length;Journal of Cell Biology;2024-06-10

4. Numb positively regulates Hedgehog signaling at the ciliary pocket;Nature Communications;2024-04-25

5. Craniofacial bone anomalies related to cholesterol synthesis defects;Scientific Reports;2024-03-04

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