Bak Activation for Apoptosis Involves Oligomerization of Dimers via Their α6 Helices
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology
Reference23 articles.
1. The Bcl-2-regulated apoptosis switch: mechanism and therapeutic potential;Adams;Curr. Opin. Immunol.,2007
2. Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis;Annis;EMBO J.,2005
3. Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis;Dewson;J. Cell Sci.,2009
4. To trigger apoptosis Bak exposes its BH3 domain and homo-dimerizes via BH3:grooove interactions;Dewson;Mol. Cell,2008
5. Zinc inhibits Bax and Bak activation and cytochrome c release induced by chemical inducers of apoptosis, but not by death-receptor-initiated pathways;Ganju;Cell Death Differ.,2003
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