Kinetic Basis for DNA Target Specificity of CRISPR-Cas12a
Author:
Funder
NIGMS
Welch Foundation
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology
Reference49 articles.
1. Lessons from enzyme kinetics reveal specificity principles for RNA-guided nucleases in RNA interference and CRISPR-based genome editing;Bisaria;Cell Syst.,2017
2. High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding;Boyle;Proc. Natl. Acad. Sci. USA,2017
3. Non-homologous DNA end joining and alternative pathways to double-strand break repair;Chang;Nat. Rev. Mol. Cell Biol.,2017
4. CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity;Chen;Science,2018
5. The crystal structure of Cpf1 in complex with CRISPR RNA;Dong;Nature,2016
Cited by 200 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Combining Off‐flow, a Nextflow‐coded program, and whole genome sequencing reveals unintended genetic variation in CRISPR/Cas-edited iPSCs;Computational and Structural Biotechnology Journal;2024-12
2. Interpretable model of CRISPR–Cas9 enzymatic reactions;Nature Computational Science;2023-12-14
3. Unleashing the potential of CRISPR multiplexing: Harnessing Cas12 and Cas13 for precise gene modulation in eye diseases;Vision Research;2023-12
4. CRISPR-Cas12a exhibits metal-dependent specificity switching;2023-11-29
5. Rapid in situ RNA imaging based on Cas12a thrusting strand displacement reaction;Nucleic Acids Research;2023-11-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"全球学者库"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前全球学者库共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2023 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3