Kinetic Basis for DNA Target Specificity of CRISPR-Cas12a
Author:
Funder
NIGMS
Welch Foundation
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology
Reference49 articles.
1. Lessons from enzyme kinetics reveal specificity principles for RNA-guided nucleases in RNA interference and CRISPR-based genome editing;Bisaria;Cell Syst.,2017
2. High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding;Boyle;Proc. Natl. Acad. Sci. USA,2017
3. Non-homologous DNA end joining and alternative pathways to double-strand break repair;Chang;Nat. Rev. Mol. Cell Biol.,2017
4. CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity;Chen;Science,2018
5. The crystal structure of Cpf1 in complex with CRISPR RNA;Dong;Nature,2016
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