Role of an invariant lysine residue in folate binding on Escherichia coli thymidylate synthase: Calorimetric and crystallographic analysis of the K48Q mutant-Reference-Cited by-同舟云学术

Role of an invariant lysine residue in folate binding on Escherichia coli thymidylate synthase: Calorimetric and crystallographic analysis of the K48Q mutant

Published:2008-01 Issue:10 Volume:40 Page:2206-2217
ISSN:1357-2725
Container-title:The International Journal of Biochemistry & Cell Biology
language:en
Short-container-title:The International Journal of Biochemistry & Cell Biology

Author:

Arvizu-Flores Aldo A.,Sugich-Miranda Rocio,Arreola Rodrigo,Garcia-Orozco Karina D.,Velazquez-Contreras Enrique F.,Montfort William R.,Maley Frank,Sotelo-Mundo Rogerio R.

Publisher

Elsevier BV

Subject

Cell Biology,Biochemistry

Reference48 articles.

1. The structural mechanism for half-the-sites reactivity in an enzyme, thymidylate synthase, involves a relay of changes between subunits;Anderson;Biochemistry,1999

2. Molecular organization, catalytic mechanism and function of serine hydroxymethyltransferase—a potential target for cancer chemotherapy;Appaji Rao;International Journal of Biochemistry & Cell Biology,2000

3. Arendall, W. B. I. (2001). X-ray structures of novel intermediates in the thymidylate synthase models for chemical mechanism and conformational change. Doctoral dissertation. Department of Biochemistry (p. 148). Tucson, AZ, USA: The University of Arizona.

4. Myeloprotection with drug-resistance genes;Banerjee;Lancet Oncology,2002

5. Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase;Banerjee;Biochimica et Biophysica Acta,2002

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4. A novel thymidylate synthase from the Vibrionales, Alteromonadales, Aeromonadales, and Pasteurellales (VAAP) clade with altered nucleotide and folate binding sites;PeerJ;2018-06-15

5. Bacterial Thymidylate Synthase Binds Two Molecules of Substrate and Cofactor without Cooperativity;Journal of the American Chemical Society;2015-11-09