Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: Exploration of 7′-substitution of benzothiadiazine-Reference-Cited by-同舟云学术

Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: Exploration of 7′-substitution of benzothiadiazine

Published:2008-02 Issue:4 Volume:18 Page:1413-1418
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Zhou Yuefen,Webber Stephen E.,Murphy Douglas E.,Li Lian-Sheng,Dragovich Peter S.,Tran Chinh V.,Sun Zhongxiang,Ruebsam Frank,Shah Amit M.,Tsan Mei,Showalter Richard E.,Patel Rupal,Li Bin,Zhao Qiang,Han Qing,Hermann Thomas,Kissinger Charles R.,LeBrun Laurie,Sergeeva Maria V.,Kirkovsky Leo

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference23 articles.

1. The burden of hepatitis C in the United States

2. The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994

3. Peginterferon and Ribavirin for Chronic Hepatitis C

4. Transmission of Hepatitis C by Intrahepatic Inoculation with Transcribed RNA

5. Recent Progress in the Development of Inhibitors of the Hepatitis C Virus RNA-Dependent RNA Polymerase

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