Synthesis of [11C]HG-10-102-01 as a new potential PET agent for imaging of LRRK2 enzyme in Parkinson’s disease-Reference-Cited by-同舟云学术

Synthesis of [11C]HG-10-102-01 as a new potential PET agent for imaging of LRRK2 enzyme in Parkinson’s disease

Published:2017-03 Issue:6 Volume:27 Page:1351-1355
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Wang Min,Gao Mingzhang,Xu Zhidong,Zheng Qi-Huang

Funder

Indiana State Department of Health (ISDH) Indiana Spinal Cord & Brain Injury FundIndiana State Department of Health (ISDH) Indiana Spinal Cord & Brain Injury Fund

United States National Science Foundation (NSF) Major Research Instrumentation ProgramUnited States National Science Foundation (NSF) Major Research Instrumentation Program (MRI)

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference48 articles.

1. Dopamine

2. Dopamine receptor mapping with PET imaging in Parkinson’s disease

3. Brain Penetrant LRRK2 Inhibitor

4. Discovery of a Pyrrolopyrimidine (JH-II-127), a Highly Potent, Selective, and Brain Penetrant LRRK2 Inhibitor

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