Design, synthesis, biological evaluation and docking study of 4-isochromanone hybrids bearing N-benzyl pyridinium moiety as dual binding site acetylcholinesterase inhibitors-Reference-Cited by-同舟云学术

Design, synthesis, biological evaluation and docking study of 4-isochromanone hybrids bearing N-benzyl pyridinium moiety as dual binding site acetylcholinesterase inhibitors

Published:2015-11 Issue:22 Volume:25 Page:5212-5216
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Wang Chaolei,Wu Zheng,Cai Hao,Xu Shengtao,Liu Jie,Jiang Jieyun,Yao Hequan,Wu Xiaoming,Xu Jinyi

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference32 articles.

1. Alzheimer's Disease

2. A Century of Alzheimer's Disease

3. Multi-Target-Directed Drug Design Strategy: From a Dual Binding Site Acetylcholinesterase Inhibitor to a Trifunctional Compound against Alzheimer’s Disease

4. Global prevalence of dementia: a Delphi consensus study

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