Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors-Reference-Cited by-同舟云学术

Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors

Published:2018-06 Issue:10 Volume:28 Page:1811-1816
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Bennett Michael J.,Wu Yiqin,Boloor Amogh,Matuszkiewicz Jennifer,O'Connell Shawn M.,Shi Lihong,Stansfield Ryan K.,Del Rosario Joselyn R.,Veal James M.,Hosfield David J.,Xu Jiangchun,Kaldor Stephen W.,Stafford Jeffrey A.,Betancort Juan M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference28 articles.

1. Bromodomains: Structure, function and pharmacology of inhibition

2. The molecular hallmarks of epigenetic control

3. Targeting the histone orthography of cancer: drugs for writers, erasers and readers

4. Structural features and inhibitors of bromodomains

5. Targeting bromodomains: epigenetic readers of lysine acetylation

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