Renin inhibitors for the treatment of hypertension: Design and optimization of a novel series of tertiary alcohol-bearing piperidines-Reference-Cited by-同舟云学术

Renin inhibitors for the treatment of hypertension: Design and optimization of a novel series of tertiary alcohol-bearing piperidines

Published:2011-07 Issue:13 Volume:21 Page:3976-3981
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Chen Austin,Cauchon Elizabeth,Chefson Amandine,Dolman Sarah,Ducharme Yves,Dubé Daniel,Falgueyret Jean-Pierre,Fournier Pierre-André,Gagné Sébastien,Gallant Michel,Grimm Erich,Han Yongxin,Houle Robert,Huang Jing-Qi,Hughes Gregory,Jûteau Hélène,Lacombe Patrick,Lauzon Sophie,Lévesque Jean-François,Liu Susana,MacDonald Dwight,Mackay Bruce,McKay Dan,Percival M. David,St-Jacques René,Toulmond Sylvie

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference9 articles.

1. http://ucatlas.ucsc.edu/cause.php

2. Drugs targeting the renin–angiotensin–aldosterone system

3. Direct renin inhibition and the kidney

4. Chen, A.; Campeau, L.-C.; Cauchon, E.; Chefson, A.; Ducharme, Y.; Dubé, D.; Falgueyret, J.-P.; Fournier, P.-A.; Gagné, S.; Grimm, E.; Han, Y.; Houle, R.; Huang, J.-Q,; Lacombe, P.; Laliberté, S.; Lévesque, J.-F.; Liu, S.; MacDonald, D.; Mackay, B.; McKay, D.; Percival, M. D.; Regan, C.; Regan, H.; St-Jacques, R.; Stump, G.; Soisson, S.; Toulmond, S. Bioorg. Med. Chem. Lett. 2011. doi:10.1016/j.bmcl.2011.05.013.

5. Piperidine-based renin inhibitors: Upper chain optimization

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Development of In Silico Models for Predicting Potential Time-Dependent Inhibitors of Cytochrome P450 3A4;Molecular Pharmaceutics;2022-12-02

2. Multi-algorithm based machine learning and structural pattern studies for hERG ion channel blockers mediated cardiotoxicity prediction;Chemometrics and Intelligent Laboratory Systems;2021-01

3. Spiropiperidines;Privileged Structures in Drug Discovery;2018-03-09

4. 4-(Hetero)Arylpiperidines;Privileged Structures in Drug Discovery;2018-03-09

5. Synthesis and fungicidal activity of 1,1-diaryl tertiary alcohols;Bioorganic & Medicinal Chemistry Letters;2016-12