Discovery of β-d-2′-deoxy-2′-α-fluoro-4′-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases-Reference-Cited by-同舟云学术

Discovery of β-d-2′-deoxy-2′-α-fluoro-4′-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases

Published:2015-06 Issue:12 Volume:25 Page:2484-2487
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Clarke Michael O.,Mackman Richard,Byun Daniel,Hui Hon,Barauskas Ona,Birkus Gabriel,Chun Byoung-Kwon,Doerffler Edward,Feng Joy,Karki Kapil,Lee Gary,Perron Michel,Siegel Dustin,Swaminathan Swami,Lee William

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference19 articles.

1. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

2. Randomized Controlled Multicenter Trial of Aerosolized Ribavirin for Respiratory Syncytial Virus Upper Respiratory Tract Infection in Hematopoietic Cell Transplant Recipients

3. Respiratory Syncytial Virus Infection in Elderly and High-Risk Adults

4. Mitochondrial toxicity of antiviral drugs

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2. Discovery and Synthesis of GS-7682, a Novel Prodrug of a 4′-CN-4-Aza-7,9-DideazaadenosineC-Nucleoside with Broad-Spectrum Potency Against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys;2024-04-19

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4. Respiratory Syncytial Virus;RNA Viruses Infection;2022-11-02

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