Potent pyrimidinetrione-based inhibitors of MMP-13 with enhanced selectivity over MMP-14-Reference-Cited by-同舟云学术

Potent pyrimidinetrione-based inhibitors of MMP-13 with enhanced selectivity over MMP-14

Published:2005-04 Issue:7 Volume:15 Page:1807-1810
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Blagg Julian A.,Noe Mark C.,Wolf-Gouveia Lilli A.,Reiter Lawrence A.,Laird Ellen R.,Chang Shang-Poa P.,Danley Dennis E.,Downs James T.,Elliott Nancy C.,Eskra James D.,Griffiths Richard J.,Hardink Joel R.,Haugeto Amber I.,Jones Christopher S.,Liras Jennifer L.,Lopresti-Morrow Lori L.,Mitchell Peter G.,Pandit Jayvardhan,Robinson Ralph P.,Subramanyam Chakrapani,Vaughn-Bowser Marcie L.,Yocum Sue A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Pyran-containing sulfonamide hydroxamic acids: potent MMP inhibitors that spare MMP-1

2. Metalloproteinases: their role in arthritis and potential as therapeutic targets

3. Phase I trial of Marimastat, a novel matrix metalloproteinase inhibitor, administered orally to patients with advanced lung cancer.

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