Pyran-containing sulfonamide hydroxamic acids: potent MMP inhibitors that spare MMP-1-Reference-Cited by-同舟云学术

Pyran-containing sulfonamide hydroxamic acids: potent MMP inhibitors that spare MMP-1

Published:2004-07 Issue:13 Volume:14 Page:3389-3395
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Reiter Lawrence A.,Robinson Ralph P.,McClure Kim F.,Jones Christopher S.,Reese Matthew R.,Mitchell Peter G.,Otterness Ivan G.,Bliven Marcia L.,Liras Jennifer,Cortina Santo R.,Donahue Kathleen M.,Eskra James D.,Griffiths Richard J.,Lame Mary E.,Lopez-Anaya Arturo,Martinelli Gary J.,McGahee Shunda M.,Yocum Sue A.,Lopresti-Morrow Lori L.,Tobiassen Lisa M.,Vaughn-Bowser Marcie L.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference49 articles.

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2. Oral administration of a matrix metalloproteinase inhibitor, CGS 27023A, protects the cartilage proteoglycan matrix in a partial meniscectomy model of osteoarthritis in rabbits

3. Discovery of CGS 27023A, a Non-Peptidic, Potent, and Orally Active Stromelysin Inhibitor That Blocks Cartilage Degradation in Rabbits

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