Efficient synthesis and cell-based silencing activity of siRNAS that contain triazole backbone linkages-Reference-Cited by-同舟云学术

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Efficient synthesis and cell-based silencing activity of siRNAS that contain triazole backbone linkages

Published:2012-02 Issue:4 Volume:22 Page:1722-1726
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Efthymiou Tim C.,Huynh Vanthi,Oentoro Jaymie,Peel Brandon,Desaulniers Jean-Paul

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference43 articles.

1. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

2. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

3. ATP Requirements and Small Interfering RNA Structure in the RNA Interference Pathway

4. 2′-Carbohydrate modifications in antisense oligonucleotide therapy: importance of conformation, configuration and conjugation

5. Chemical modification: the key to clinical application of RNA interference?

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1. Recent advances in the synthesis of cholesterol-based triazoles and their biological applications;Steroids;2024-11

2. Advances and prospects of RNA delivery nanoplatforms for cancer therapy;Acta Pharmaceutica Sinica B;2024-09

3. Synthesis of Dinucleotide Non‐Symmetrical Triester Phosphate Phosphoramidites and Their Incorporation Within Oligonucleotides;Current Protocols;2023-05

4. SiRNAs with Neutral Phosphate Triester Hydrocarbon Tails Exhibit Carrier-Free Gene-Silencing Activity;ACS Medicinal Chemistry Letters;2022-03-14

5. Building siRNAs with Cubes: Synthesis and Evaluation of Cubane‐Modified siRNAs;ChemBioChem;2021-08-11

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