SiRNAs with Neutral Phosphate Triester Hydrocarbon Tails Exhibit Carrier-Free Gene-Silencing Activity-Reference-Cited by-同舟云学术

SiRNAs with Neutral Phosphate Triester Hydrocarbon Tails Exhibit Carrier-Free Gene-Silencing Activity

Published:2022-03-14 Issue:4 Volume:13 Page:695-700
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Hammill Matthew L.¹,Tsubaki Kouta¹²,Salim Lidya¹,Varley Andrew J.¹,Giorgees Ifrodet¹,Kitamura Mitsuru²,Okauchi Tatsuo²^ORCID,Desaulniers Jean-Paul¹^ORCID

Affiliation:

1. Faculty of Science, University of Ontario Institute of Technology, 2000 Simcoe Street North, Oshawa, Ontario L1G 0C5, Canada

2. Department of Applied Chemistry, Graduate School of Engineering, Kyushu Institute of Technology, 1-1 Sensui-cho, Tobata, Kitakyushu 804-8550, Japan

Funder

Natural Sciences and Engineering Research Council of Canada

Institute of Rheological Functions of Food

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.2c00027

Reference30 articles.

1. RNA interference

2. Molecular Basis for Target RNA Recognition and Cleavage by Human RISC