The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist-Reference-Cited by-同舟云学术

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The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist

Published:2008-12 Issue:23 Volume:18 Page:6097-6099
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Madauss Kevin P.,Bledsoe Randy K.,Mclay Iain,Stewart Eugene L.,Uings Iain J.,Weingarten Gordon,Williams Shawn P.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Drug Insight: selective agonists and antagonists of the glucocorticoid receptor

2. Dissociated non-steroidal glucocorticoids: tuning out untoward effects

3. Dissociated non-steroidal glucocorticoid receptor modulators: an update on new compounds

4. Nonsteroidal Glucocorticoid Agonists: Tetrahydronaphthalenes with Alternative Steroidal A-Ring Mimetics Possessing Dissociated (Transrepression/Transactivation) Efficacy Selectivity

5. Non-steroidal glucocorticoid agonists—The discovery of aryl pyrazoles as A-ring mimetics

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1. Chemical space exploration with Molpher: Generating and assessing a glucocorticoid receptor ligand library;Molecular Informatics;2024-07-09

2. Impact of atropisomerism on a non-steroidal glucocorticoid receptor agonist;RSC Medicinal Chemistry;2024

3. Discriminating functional and non-functional nuclear-receptor ligands with a conformational selection-inspired machine learning algorithm;Cell Reports Physical Science;2023-07

4. The Biologist’s Guide to the Glucocorticoid Receptor’s Structure;Cells;2023-06-15

5. Selective Glucocorticoid Receptor Modulators;SpringerBriefs in Molecular Science;2023

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