Identification and SAR around N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective α2C adrenergic receptor antagonist-Reference-Cited by-同舟云学术

Identification and SAR around N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective α2C adrenergic receptor antagonist

Published:2008-10 Issue:20 Volume:18 Page:5689-5693
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Patel Snahel D.,Habeski Wendy M.,Min Hyunsuk,Zhang Jiansu,Roof Robin,Snyder Bradley,Bora Gary,Campbell Brian,Li Cheryl,Hidayetoglu Debra,Johnson Douglas S.,Chaudhry Archana,Charlton Maura E.,Kablaoui Natasha M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Clinical Uses of α2-Adrenergic Agonists

2. SNaRIs, NaSSAs, and NaRIs: new agents for the treatment of depression

3. Evaluation of the α2C-adrenoceptor as a neuropsychiatric drug target

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