A versatile catalyst system for enantioselective synthesis of 2-substituted 1,4-benzodioxanes

Author:

Chong Eugene123ORCID,Qu Bo123ORCID,Zhang Yongda123ORCID,Cannone Zachary P.123,Leung Joyce C.123,Tcyrulnikov Sergei453,Nguyen Khoa D.123ORCID,Haddad Nizar123,Biswas Soumik123,Hou Xiaowen123,Kaczanowska Katarzyna678,Chwalba Michał678,Tracz Andrzej678,Czarnocki Stefan678,Song Jinhua J.123,Kozlowski Marisa C.453ORCID,Senanayake Chris H.123910

Affiliation:

1. Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc.

2. Ridgefield

3. USA

4. Department of Chemistry

5. University of Pennsylvania Philadelphia

6. Apeiron Synthesis S.A. Wroclaw Technology Park ul

7. 54-427 Wrocław

8. Poland

9. Astatech BioPharmaceutical Corporation

10. Chengdu

Abstract

IrCl/BIDIME-dimer catalyzed hydrogenation is reported for enantioselective synthesis of 2-substituted 1,4-benzodioxanes.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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