N-Alkylpyrido[1′,2′:1,5]pyrazolo-[4,3-d]pyrimidin-4-amines: A new series of negative allosteric modulators of mGlu1/5 with CNS exposure in rodents-Reference-Cited by-同舟云学术

N-Alkylpyrido[1′,2′:1,5]pyrazolo-[4,3-d]pyrimidin-4-amines: A new series of negative allosteric modulators of mGlu1/5 with CNS exposure in rodents

Published:2016-04 Issue:8 Volume:26 Page:1894-1900
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Felts Andrew S.,Rodriguez Alice L.,Morrison Ryan D.,Venable Daryl F.,Blobaum Anna L.,Byers Frank W.,Daniels J. Scott,Niswender Colleen M.,Jones Carrie K.,Conn P. Jeffrey,Lindsley Craig W.,Emmitte Kyle A.

Funder

NIMH

NIDA

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference74 articles.

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2. Pharmacological agents acting at subtypes of metabotropic glutamate receptors

3. PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS

4. Allosteric Modulation of Seven Transmembrane Spanning Receptors: Theory, Practice, and Opportunities for Central Nervous System Drug Discovery

5. Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

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