Synthesis and optimization of arylsulfonylpiperazines as a novel class of inhibitors of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)-Reference-Cited by-同舟云学术

Synthesis and optimization of arylsulfonylpiperazines as a novel class of inhibitors of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)

Published:2009-03 Issue:5 Volume:19 Page:1522-1527
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Sun Daqing,Wang Zhulun,Cardozo Mario,Choi Rebekah,DeGraffenreid Michael,Di Yongmei,He Xiao,Jaen Juan C.,Labelle Marc,Liu Jinsong,Ma Ji,Miao Shichang,Sudom Athena,Tang Liang,Tu Hua,Ursu Stefania,Walker Nigel,Yan Xuelei,Ye Qiuping,Powers Jay P.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference21 articles.

1. 11β-Hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action

2. Inhibition of 11β-HSD1 as a novel treatment for the metabolic syndrome: do glucocorticoids play a role?

3. Novel Adipose Tissue–Mediated Resistance to Diet-Induced Visceral Obesity in 11β-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice

4. 11β-Hydroxysteroid Dehydrogenase Type 1: A Tissue-Specific Regulator of Glucocorticoid Response

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