Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK)-Reference-Cited by-同舟云学术

Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK)

Published:2013-12 Issue:23 Volume:23 Page:6331-6335
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

MacKinnon Colin H.,Lau Kevin,Burch Jason D.,Chen Yuan,Dines Jonathon,Ding Xiao,Eigenbrot Charles,Heifetz Alexander,Jaochico Allan,Johnson Adam,Kraemer Joachim,Kruger Susanne,Krülle Thomas M.,Liimatta Marya,Ly Justin,Maghames Rosemary,Montalbetti Christian A.G.N.,Ortwine Daniel F.,Pérez-Fuertes Yolanda,Shia Steven,Stein Daniel B.,Trani Giancarlo,Vaidya Darshan G.,Wang Xiaolu,Bromidge Steven M.,Wu Lawren C.,Pei Zhonghua

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference24 articles.

1. Tec Kinases in T Cell and Mast Cell Signaling

2. T‐cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man

3. Attenuation of Immunological Symptoms of Allergic Asthma in Mice Lacking the Tyrosine Kinase ITK

4. Requirement for Tec Kinases Rlk and Itk in T Cell Receptor Signaling and Immunity

5. Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors

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