Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors-Reference-Cited by-同舟云学术

Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors

Published:2006-05 Issue:9 Volume:16 Page:2411-2415
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Das Jagabandhu,Liu Chunjian,Moquin Robert V.,Lin James,Furch Joseph A.,Spergel Steven H.,McIntyre Kim W.,Shuster David J.,O’Day Kathleen D.,Penhallow Becky,Hung Chen-Yi,Kanner Steven B.,Lin Tai-An,Dodd John H.,Barrish Joel C.,Wityak John

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

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2. Signal Transduction Mediated by the T Cell Antigen Receptor: The Role of Adapter Proteins

3. T-cell signalling and autoimmunity: molecular mechanisms of disease

4. The Tec family of tyrosine kinases in T cells, amplifiers of T cell receptor signals

5. Tec family kinases in lymphocyte signaling and function

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