NMS-P937, a 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivative as potent and selective Polo-like kinase 1 inhibitor-Reference-Cited by-同舟云学术

NMS-P937, a 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivative as potent and selective Polo-like kinase 1 inhibitor

Published:2011-05 Issue:10 Volume:21 Page:2969-2974
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Beria Italo,Bossi Roberto T.,Brasca Maria Gabriella,Caruso Michele,Ceccarelli Walter,Fachin Gabriele,Fasolini Marina,Forte Barbara,Fiorentini Francesco,Pesenti Enrico,Pezzetta Daniele,Posteri Helena,Scolaro Alessandra,Depaolini Stefania Re,Valsasina Barbara

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference14 articles.

1. Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

2. A Phase I Pharmacokinetic Study of HMN-214, a Novel Oral Stilbene Derivative with Polo-Like Kinase-1–Interacting Properties, in Patients with Advanced Solid Tumors

3. Use of the Novel Plk1 Inhibitor ZK-Thiazolidinone to Elucidate Functions of Plk1 in Early and Late Stages of Mitosis

4. Polo-like kinases and the orchestration of cell division

5. Polo-like Kinase-1 Is Required for Bipolar Spindle Formation but Is Dispensable for Anaphase Promoting Complex/Cdc20 Activation and Initiation of Cytokinesis

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