Discovery and SAR of substituted 3-oxoisoindoline-4-carboxamides as potent inhibitors of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer-Reference-Cited by-同舟云学术

Discovery and SAR of substituted 3-oxoisoindoline-4-carboxamides as potent inhibitors of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer

Published:2010-02 Issue:3 Volume:20 Page:1023-1026
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Gandhi Viraj B.,Luo Yan,Liu Xuesong,Shi Yan,Klinghofer Vered,Johnson Eric F.,Park Chang,Giranda Vincent L.,Penning Thomas D.,Zhu Gui-Dong

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference26 articles.

1. The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors

2. Docking studies on PARP-1 inhibitors: insights into the role of a binding pocket water molecule

3. Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors

4. Novel poly(ADP-ribose) polymerase-1 inhibitors

5. Novel alkoxybenzamide inhibitors of poly(ADP-ribose) polymerase

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