Novel alkoxybenzamide inhibitors of poly(ADP-ribose) polymerase-Reference-Cited by-同舟云学术

Novel alkoxybenzamide inhibitors of poly(ADP-ribose) polymerase

Published:2008-07 Issue:14 Volume:18 Page:3942-3945
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Menear Keith A.,Adcock Claire,Alonso Francisco Cuenca,Blackburn Kristel,Copsey Louise,Drzewiecki Jan,Fundo Alexandra,Le Gall Armelle,Gomez Sylvie,Javaid Hashim,Lence Carlos Fenandez,Martin Niall M.B.,Mydlowski Chris,Smith Graeme C.M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference11 articles.

1. Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors

2. Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite.

3. Hydrogen peroxide insult in cultured mammalian cells: relationships between DNA single-strand breakage, poly(ADP-ribose) metabolism and cell killing

4. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

5. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Cited by 38 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Targeting NAD Metabolism: Rational Design, Synthesis and In Vitro Evaluation of NAMPT/PARP1 Dual-Target Inhibitors as Anti-Breast Cancer Agents;Molecules;2024-06-14

2. Design and synthesis of the first PARP-1 and proteasome dual inhibitors to treat breast cancer;European Journal of Medicinal Chemistry;2024-01

3. Ovarian cancer treatment strategies: focus on PARP inhibitors;International Conference on Modern Medicine and Global Health (ICMMGH 2023);2023-09-07

4. Development of novel conformationally restricted selective Clk1/4 inhibitors through creating an intramolecular hydrogen bond involving an imide linker;European Journal of Medicinal Chemistry;2022-08

5. Modulating physicochemical properties of tetrahydropyridine-2-amine BACE1 inhibitors with electron-withdrawing groups: A systematic study;European Journal of Medicinal Chemistry;2022-01