Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration-Reference-Cited by-同舟云学术

Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration

Published:2011-09 Issue:18 Volume:21 Page:5521-5527
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Bowers Simeon,Truong Anh P.,Jeffrey Neitz R.,Hom Roy K.,Sealy Jennifer M.,Probst Gary D.,Quincy David,Peterson Brian,Chan Wayman,Galemmo Robert A.,Konradi Andrei W.,Sham Hing L.,Tóth Gergely,Pan Hu,Lin May,Yao Nanhua,Artis Dean R.,Zhang Heather,Chen Linda,Dryer Mark,Samant Bhushan,Zmolek Wes,Wong Karina,Lorentzen Colin,Goldbach Erich,Tonn George,Quinn Kevin P.,Sauer John-Michael,Wright Sarah,Powell Kyle,Ruslim Lany,Ren Zhao,Bard Frédérique,Yednock Ted A.,Griswold-Prenner Irene

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference32 articles.

1. Small Molecule JNK (c-Jun N-Terminal Kinase) Inhibitors

2. c-Jun N-terminal kinase (JNK) signaling: Recent advances and challenges

3. Specific activities of individual c-Jun N-terminal kinases in the brain

4. Inhibitors of c-jun-N-Terminal Kinase (JNK)

5. Inhibitors of c-Jun N-terminal kinases—JuNK no more?

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