Small Molecule JNK (c-Jun N-Terminal Kinase) Inhibitors
Author:
Affiliation:
1. Merck Research Laboratories, 320 Bent Street, Cambridge, Massachusetts 02141
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm9003279
Reference65 articles.
1. Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases
2. JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
3. Phosphorylation of c-jun mediated by MAP kinases
4. JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation.
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