Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)-Reference-Cited by-同舟云学术

Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)

Published:2015-03 Issue:6 Volume:25 Page:1310-1317
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Martín-Martín María Luz,Bartolomé-Nebreda José Manuel,Conde-Ceide Susana,Alonso de Diego Sergio A.,López Silvia,Martínez-Viturro Carlos M.,Tong Han Min,Lavreysen Hilde,Macdonald Gregor J.,Steckler Thomas,Mackie Claire,Bridges Thomas M.,Daniels J. Scott,Niswender Colleen M.,Noetzel Meredith J.,Jones Carrie K.,Conn P. Jeffrey,Lindsley Craig W.,Stauffer Shaun R.

Funder

Janssen Pharmaceutical Companies of Johnson & Johnson

NIH

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference41 articles.

1. Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

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