Development of a simple proton nuclear magnetic resonance-based procedure to estimate the approximate distribution coefficient at physiological pH (log D 7.4 ): Evaluation and comparison to existing practices-Reference-Cited by-同舟云学术

Development of a simple proton nuclear magnetic resonance-based procedure to estimate the approximate distribution coefficient at physiological pH (log D 7.4 ): Evaluation and comparison to existing practices

Published:2017-01 Issue:2 Volume:27 Page:319-322
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Stéen E. Johanna L.,Nyberg Nils,Lehel Szabolcs,Andersen Valdemar L.,Di Pilato Pantaleo,Knudsen Gitte M.,Kristensen Jesper L.,Herth Matthias M.

Funder

Lundbeck Foundation

University of Copenhagen

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference16 articles.

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2. QSAR and ADME

3. Lipophilicity in drug discovery

4. A Structural Analogue Approach to the Prediction of the Octanol−Water Partition Coefficient

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