Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes-Reference-Cited by-同舟云学术

Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes

Published:2006-07 Issue:14 Volume:16 Page:3679-3683
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Yan Lin,Huo Pei,Doherty George,Toth Lesile,Hale Jeffrey J.,Mills Sander G.,Hajdu Richard,Keohane Carol A.,Rosenbach Mark J.,Milligan James A.,Shei Gan-Ju,Chrebet Gary,Bergstrom James,Card Deborah,Quackenbush Elizabeth,Wickham Alexandra,Mandala Suzanne M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. Signaling and biological actions of sphingosine 1-phosphate

2. Synthesis and Immunosuppressive Activity of 2-Substituted 2-Aminopropane-1,3-diols and 2-Aminoethanols

3. FTY720: early clinical experience

4. Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720

5. Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically Active Species and Its Enantiomer

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of Tricyclic Agonists of Sphingosine-1-phosphate Receptor 1 (S1P1) Employing Ligand-Based Drug Design;Journal of Medicinal Chemistry;2016-10-20

2. Discovery of Tetrahydropyrazolopyridine as Sphingosine 1-Phosphate Receptor 3 (S1P3)-Sparing S1P1 Agonists Active at Low Oral Doses;Journal of Medicinal Chemistry;2016-01-22

3. PREPARATION OF 1,2,4-OXADIAZOLES: TEACHING-LEARNING SEQUENCE APPLIED TO THE COURSE ON ORGANIC SYNTHESIS IN UNDERGRADUATE STUDIES;Química Nova;2016

4. Optimization of Sphingosine-1-phosphate-1 Receptor Agonists: Effects of Acidic, Basic, and Zwitterionic Chemotypes on Pharmacokinetic and Pharmacodynamic Profiles;Journal of Medicinal Chemistry;2014-12-15

5. A novel one-pot synthesis of ferrocenyl-substituted 1,2,4-oxadiazoles;Journal of Organometallic Chemistry;2014-06