Expedited SAR study of high-affinity ligands to the α2δ subunit of voltage-gated calcium channels: Generation of a focused library using a solution-phase Sn2Ar coupling methodology-Reference-Cited by-同舟云学术

Expedited SAR study of high-affinity ligands to the α2δ subunit of voltage-gated calcium channels: Generation of a focused library using a solution-phase Sn2Ar coupling methodology

Published:2006-02 Issue:3 Volume:16 Page:746-749
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Chen Chixu,Stearns Brian,Hu Tao,Anker Naomi,Santini Angelina,Arruda Jeannie M.,Campbell Brian T.,Datta Purabi,Aiyar Jayashree,Munoz Benitio

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference24 articles.

1. 3-Substituted GABA analogs with central nervous system activity: A review

2. Taylor, C. P. The Role of Gabapentin. In Epilepsy Management, Chadwick, D., Ed.; Royal Society of Medicine Service Ltd.: London, 1993; p 13.

3. The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain

4. The anticonvulsant compound gabapentin possesses anxiolytic but not amnesic effects in rats

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Towards Multitargeted Ligands as Pain Therapeutics: Dual Ligands of the Ca_vα2δ‐1 Subunit of Voltage‐Gated Calcium Channel and the μ‐Opioid Receptor;ChemMedChem;2024-01-17

2. Bicyclic Diazepinones as Dual Ligands of the α2δ-1 Subunit of Voltage-Gated Calcium Channels and the Norepinephrine Transporter;Journal of Medicinal Chemistry;2021-02-16

3. Synthesis of Novel Gabapentin Scaffold Derived Hydrazide-hydrazones for Potential Antimicrobial agents and Antioxidants;Chemistry Africa;2020-09-21

4. Catalytic Friedel‐Crafts Reactions on Saturated Heterocycles and Small Rings for sp 3 ‐sp 2 Coupling of Medicinally Relevant Fragments;European Journal of Organic Chemistry;2019-06-12

5. Synthesis of isoindoles and related iso-condensed heteroaromatic pyrroles;Chemical Society Reviews;2012