Insights on the role of boron containing moieties in the design of new potent and efficient agonists targeting the β2 adrenoceptor-Reference-Cited by-同舟云学术

Insights on the role of boron containing moieties in the design of new potent and efficient agonists targeting the β2 adrenoceptor

Published:2015-02 Issue:4 Volume:25 Page:820-825
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Soriano-Ursúa Marvin A.,Arias-Montaño José A.,Correa-Basurto José,Hernández-Martínez Christian F.,López-Cabrera Yessica,Castillo-Hernández Maria C.,Padilla-Martínez Itzia I.,Trujillo-Ferrara José G.

Funder

Comisión de Operación y Fomento de Actividades Académicas

Secretaría de Investigación y Posgrado del Instituto Politécnico Nacional

Consejo Nacional de Ciencia y Tecnología de México

Programa Iberoamericano De Ciencia Y Tecnología Para El Desarrollo

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference32 articles.

1. Clinical Implications of Recent Insights into the Structural Biology of Beta2 Adrenoceptors

2. Bronchodilators

3. Pharmacogenetics of β2-Agonists

4. Cell-based and in-silico studies on the high intrinsic activity of two boron-containing salbutamol derivatives at the human β2-adrenoceptor

5. Design, synthesis and in vitro evaluation of (R)-4-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenyl hydrogen phenylboronate: A novel salbutamol derivative with high intrinsic efficacy on the β2 adrenoceptor

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