Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif-Reference-Cited by-同舟云学术

Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif

Published:2008-05 Issue:9 Volume:18 Page:2865-2870
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Kreutter Kevin D.,Lu Tianbao,Lee Lily,Giardino Edward C.,Patel Sharmila,Huang Hui,Xu Guozhang,Fitzgerald Mark,Haertlein Barbara J.,Mohan Venkatraman,Crysler Carl,Eisennagel Stephen,Dasgupta Malini,McMillan Martin,Spurlino John C.,Huebert Norman D.,Maryanoff Bruce E.,Tomczuk Bruce E.,Damiano Bruce P.,Player Mark R.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Heart Disease and Stroke Statistics—2007 Update

2. Evaluation and Management of Atrial Fibrillation

3. Arginine Mimetic Structures in Biologically Active Antagonists and Inhibitors

4. The Direct Thrombin Inhibitor Melagatran and Its Oral Prodrug H 376/95: Intestinal Absorption Properties, Biochemical and Pharmacodynamic Effects

5. Structure-Based Design of Novel Potent Nonpeptide Thrombin Inhibitors

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