2,6-Disubstituted N-arylsulfonyl piperidines as γ-secretase inhibitors-Reference-Cited by-同舟云学术

2,6-Disubstituted N-arylsulfonyl piperidines as γ-secretase inhibitors

Published:2007-01 Issue:1 Volume:17 Page:57-62
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Pissarnitski Dmitri A.,Asberom Theodros,Bara Thomas A.,Buevich Alex V.,Clader John W.,Greenlee William J.,Guzik Henry S.,Josien Hubert B.,Li Wei,McEwan Michael,McKittrick Brian A.,Nechuta Terry L.,Parker Eric M.,Sinning Lisa,Smith Elizabeth M.,Song Lixin,Vaccaro Henry A.,Voigt Johannes H.,Zhang Lili,Zhang Qi,Zhao Zhiqiang

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Alzheimer's Disease: Molecular Understanding Predicts Amyloid-Based Therapeutics

2. Secretase Targets for Alzheimer's Disease: Identification and Therapeutic Potential

3. Identity and function of ?-secretase

4. Synthesis of biotinylated photoaffinity probes based on arylsulfonamide γ-secretase inhibitors

5. 4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors

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