4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors-Reference-Cited by-同舟云学术

4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors

Published:2006-01 Issue:2 Volume:16 Page:280-284
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Churcher Ian,Beher Dirk,Best Jonathan D.,Castro José L.,Clarke Earl E.,Gentry Amy,Harrison Timothy,Hitzel Laure,Kay Euan,Kerrad Sonia,Lewis Huw D.,Morentin-Gutierrez Pablo,Mortishire-Smith Russell,Oakley Paul J.,Reilly Michael,Shaw Duncan E.,Shearman Mark S.,Teall Martin R.,Williams Susie,Wrigley Jonathan D.J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference23 articles.

1. Structure and function of amyloid in Alzheimer's disease

2. Twenty Years of the Alzheimer’s Disease Amyloid Hypothesis: A Genetic Perspective

3. Genetic Factors in Alzheimer's Disease

4. Alzheimer's Disease: The Amyloid Cascade Hypothesis

5. The amyloid precursor protein and its network of interacting proteins: physiological and pathological implications

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