Conformationally-restricted cyclic sulfones as potent and selective mTOR kinase inhibitors-Reference-Cited by-同舟云学术

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Conformationally-restricted cyclic sulfones as potent and selective mTOR kinase inhibitors

Published:2012-08 Issue:15 Volume:22 Page:5114-5117
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Liu Kevin K.-C.,Bailey Simon,Dinh Dac M.,Lam Hieu,Li Chunze,Wells Peter A.,Yin Min-Jean,Zou Aihua

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference7 articles.

1. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

2. Growing roles for the mTOR pathway

3. The Pharmacology of mTOR Inhibition

4. Targeting mTOR signaling for cancer therapy

5. Activation of Akt and eIF4E Survival Pathways by Rapamycin-Mediated Mammalian Target of Rapamycin Inhibition

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