The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2′-α-chloro-2′-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors-Reference-Cited by-同舟云学术

The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2′-α-chloro-2′-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors

Published:2017-09 Issue:18 Volume:27 Page:4323-4330
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Alexandre François-René,Badaroux Eric,Bilello John P.,Bot Stéphanie,Bouisset Tony,Brandt Guillaume,Cappelle Sylvie,Chapron Christopher,Chaves Dominique,Convard Thierry^ORCID,Counor Clément,Da Costa Daniel,Dukhan David,Gay Marion^ORCID,Gosselin Gilles^ORCID,Griffon Jean-François,Gupta Kusum^ORCID,Hernandez-Santiago Brenda,La Colla Massimiliano,Lioure Marie-Pierre,Milhau Julien,Paparin Jean-Laurent,Peyronnet Jérôme,Parsy Christophe^ORCID,Pierra Rouvière Claire,Rahali Houcine,Rahali Rachid,Salanson Aurélien,Seifer Maria,Serra Ilaria,Standring David,Surleraux Dominique,Dousson Cyril B.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference35 articles.

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2. Diagnosis, management, and treatment of hepatitis C: An update

3. The HCV Revolution Did Not Happen Overnight

4. Evolution and emergence of a new era of antiviral treatment for chronic hepatitis C infection

5. Emerging treatments for chronic hepatitis C

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