Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening

Author:

Miles Jared A.,Kapure Jeevak S.,Deora Girdhar Singh,Courageux Charlotte,Igert AlexandreORCID,Dias José,McGeary Ross P.,Brazzolotto Xavier,Ross Benjamin P.

Funder

The University of Queensland School of Pharmacy

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. Alzheimer’s Disease International, Policy Brief for Heads of Government: The Global Impact of Dementia 2013 - 2050. Policy Brief for Heads of Government: The Global Impact of Dementia 2013–2050: 2013.

2. Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease;West;Lancet,1994

3. Alzheimer’s disease and senile dementia: loss of neurons in the basal forebrain;Whitehouse;Science,1982

4. Cholinesterase content of certain regions of the spinal cord as judged by histochemical and cartesian diver technique;Giacobini;Acta Physiol Scand,1958

5. Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity;Hartmann;J Neurochem,2007

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3