Discovery and optimization of a new class of potent and non-chiral indole-3-carboxamide-based renin inhibitors-Reference-Cited by-同舟云学术

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Discovery and optimization of a new class of potent and non-chiral indole-3-carboxamide-based renin inhibitors

Published:2010-11 Issue:21 Volume:20 Page:6268-6272
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Scheiper Bodo,Matter Hans,Steinhagen Henning,Stilz Ulrich,Böcskei Zsolt,Fleury Valérie,McCort Gary

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference26 articles.

1. Drugs targeting the renin–angiotensin–aldosterone system

2. Aliskiren: the first renin inhibitor for clinical treatment

3. Maintenance of blood pressure by the renin–angiotensin system in normal man

4. Inhibitors of Renin as Potential Therapeutic Agents

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